Transesophageal Echocardiography
Conditions
Keywords
age range of 18-83
Brief summary
There is no ideal sedation technique that can be used during Transesophageal Echocardiography (TEE), and the data concerning the effects of available sedation techniques on Heart Rate Variability (HRV) are limited. In this study the investigators aimed at comparing the effects of sedation through hypnotherapy with medical sedation achieved by midazolam on HRV.
Detailed description
Seventy-six patients with an indication of TEE will be recruited, the age range will be 18-83 years. In Group Topical (T) there are 26 patients who had the procedure under topical pharyngeal anesthesia, in Group Midazolam (D) there are 25 patients who will receive midazolam and in Group H there are 27 patients receiving hypnosis. All patients will have an IV access; throughout the procedure heart rate, rhythm ECG, peripheric O2 saturation will be monitored with a non-invasive monitor, blood pressure measurements were taken every 3 minutes. Rhythm Holter recordings will be obtained from all patients and TEE will be performed.
Interventions
DRUGlocal anesthesia
patients will receive only topical anesthesia with 1% lidocaine
BEHAVIORALhypnosis
Hypnosis will be performed by the same anesthesiologist according to indirect Erickson's method
DRUGMidazolam
Before insertion of the probe, the patients will be sedated with midazolam at a dose of 0,.05 mg/kg iv (to achieve a Ramsay Sedation Score of 2-3). If needed, additional iv doses (0.005 mg/kg) were given during the procedure.
Sponsors
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 83 Years
Healthy volunteers
No
Inclusion criteria
* Patients with a need of transesophageal echocardiography
Exclusion criteria
* Heart failure * Bad overall condition * Arrhythmia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hypnotic sedation | two months | Contrary to sedation with midazolam; when hypnosis is used for sedation in TEE patients, autonomic cardiac tone is modified to a significant extent. Hypnotic sedation achieves this by increasing the parasympathetic activity, decreasing the sympathetic activity and changing the sympathovagal interaction balance. |
Countries
Turkey (Türkiye)
Outcome results
None listed