Streptococcus Pneumoniae Nasopharyngeal Carriage
Conditions
Brief summary
The objective of this active surveillance study is to make available crucial data about epidemiology, serotype distribution, and longitudinal pattern of antibiotic susceptibility of nasopharyngeal strains of Streptococcus pneumoniae carried in the population of healthy children aged less than years and living in the area of Milan and surroundings, Lombardy, Italy. * To estimate the nasopharyngeal carriage rate and longitudinal pattern of Streptococcus pneumoniae in healthy children aged less than 5 years living in the area of Milan, Italy; * To describe the circulation of antimicrobial non-susceptible Streptococcus pneumoniae strains in healthy children aged less than 5 years Secondary objectives: * To describe the nasopharyngeal carriage distribution of Streptococcus pneumoniae strains in healthy subjects less than 5 years old; * To examine the role of risk factors in the Streptococcus pneumoniae carriage rate in healthy children; * • To evaluate the possible impact of vaccination policy in the referenced population.
Interventions
None listed
Sponsors
University of Milan
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
3 Months to 5 Years
Healthy volunteers
No
Inclusion criteria
* To estimate the nasopharyngeal carriage rate and longitudinal pattern of Streptococcus pneumoniae in healthy children aged less than 5 years living in the area of Milan, Italy; * To describe the circulation of antimicrobial non-susceptible Streptococcus pneumoniae strains in healthy children aged less than5 years
Exclusion criteria
* To describe the nasopharyngeal carriage distribution of Streptococcus pneumoniae strains in healthy subjects less than 5 years old; * To examine the role of risk factors in the Streptococcus pneumoniae carriage rate in healthy children; * To evaluate the possible impact of vaccination policy in the referenced population..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • circulation of antimicrobial non-susceptible Streptococcus pneumoniae strains in healthy children aged less than 5 years | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| • the nasopharyngeal carriage distribution of Streptococcus pneumoniae strains in healthy subjects less than 5 years old; | 1 year |
| • the role of risk factors in the Streptococcus pneumoniae carriage rate in healthy children; | 1 year |
| • the possible impact of vaccination policy in the referenced population | 1 year |
Countries
Italy
Contacts
Primary ContactGian Vincenzo Zuccotti, Professor
Outcome results
None listed