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NOMAC : New Tools for Managing the Fate of Cereal Nutrients in the Gut : Effects of Amylose Content on Glycemic Index.

NOMAC : New Tools for Managing the Fate of Cereal Nutrients in the Gut : Effects of Amylose Content on Glycemic Index.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01437917
Acronym
NOMAC
Enrollment
10
Registered
2011-09-21
Start date
2011-09-30
Completion date
2012-04-30
Last updated
2012-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

glycemic index

Brief summary

The consumption of cereals-based foods with low glycemic indexes, high micronutrients and fibers contents are highly recommended. The target of this work is to provide new solutions for cereal based foods: the knowledge and understanding on the in vivo fate will be used to define structural features to gain in foods.

Interventions

OTHER20% amylose bread

20% amylose bread

DIETARY_SUPPLEMENT10% amylose bread

10% amylose bread

DIETARY_SUPPLEMENTCarbohydrates

50g of carbohydrates ingested with 400 ml of water

Sponsors

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
CollaboratorOTHER
Rennes University Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
19 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy individual, * Age between 19-65 years * With normal food habits with at least 2 main meals per day * Non smoking * Having filled the consent form

Exclusion criteria

* BMI \> 25 kg/m2, * Diabetes or any illness susceptible to alter * Coeliac disease * Past history of intestinal diseases. * Treatment susceptible of modifying glycemia. * Allergy

Design outcomes

Primary

MeasureTime frameDescription
Glycemic index for each bread2 hoursTo compare the glycemic index of breads made with different amylose content. (S1 to S6) A total of 6 visits. In each visit, blood samples will be taken for measurement of glycemia and insulinemia over 2 hours after ingestion of 50 of carbohydrates ingested with 400 ml of water.

Secondary

MeasureTime frameDescription
AUC for insulinemia for the 2 hours following the ingestion of each bread.2 hoursTo compare the AUC for insulinemia for the 2 hours following the ingestion of each bread.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026