EFficacy of Prophylactic Clip Application in Decrease of Immediate Postpolypectomy Bleeding and Delayed Postpolypectomy Bleeding After Colonoscopic Removal for a Large Pedunculated Polyps

Does a Prophylactic Clip Application Decrease IPPB(Immediate Postpolypectomy Bleeding) and DPPB(Delayed Postpolypectomy Bleeding) After Colonoscopic Removal for a Large Pedunculated Polyps (>1cm)?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01437631

Enrollment

137

Registered

2011-09-21

Start date

2011-09-01

Completion date

2015-04-30

Last updated

2020-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polyp of Large Intestine

Keywords

colon polyp, endoscopic polypectomy, postpolypectomy bleeding, prophylactic clip application

Brief summary

The aim of this study is to evaluate the efficacy of prophylactic clip application after colonoscopic removal for a large pedunculated polyp (\> 1cm) in preventing immediate postpolypectomy bleeding (IPPB) and delayed postpolypectomy bleeding (DPPB).

Interventions

PROCEDUREprophylactic clip application

prophylactic clip application after colonoscopic polypectomy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients who have a large pedunculated polyp(\>1cm) in the colon

Exclusion criteria

* Age under 20 years * Subjects who are taking anticoagulants * Subjects who have an abnormal coagulogram (platelet count, international normalized ratio, or activated partial thromboplastin time) * Subjects who have inflammatory bowel diseases

Design outcomes

Primary

Measure	Time frame	Description
the occurrence of immediate post-polypectomy bleeding	1 day	At 1 day after endoscopic polypectomy, CBC will be done.
the occurrence of delayed post-polypectomy bleeding	2 weeks	At 2 weeks after endoscopic polypectomy, history of hematochezia will be taken at outpatient clinic.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026