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Effect of Positive End Expiratory Pressure (PEEP) on Cerebral Oxymetry During Laparoscopy

International Reveiw Board of Gachon Univerity Gil Hospital

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01436812
Enrollment
30
Registered
2011-09-20
Start date
2011-09-30
Completion date
2013-06-30
Last updated
2013-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Ischemia

Keywords

cerebral oxymetry, laparoscopy, PEEP

Brief summary

The investigators hypothesized that positive end expiratory pressure (PEEP) would increase the regional oxygen saturation (rSO2).

Detailed description

The investigators hypothesized that PEEP would increase the rSO2 during laparoscopic surgery by improving oxygenation.

Interventions

PROCEDUREzero end-expiratory pressure

positive end expiratory pressure 0 cm H2O during peumoperitoneum

PROCEDUREpositive end expiratory pressure

PEEP 0 cmH2O

Sponsors

Gachon University Gil Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* ASA PS I or II adult patient undergoing laparoscopic low anterior resection with Trendelenburg position

Exclusion criteria

* Patients with history of cerebrovascular disease, coronary occlusive disease and/or obesity (body mass index \> 30) were excluded from this study.

Design outcomes

Primary

MeasureTime frameDescription
cerebral ischemiachange from baseline in rSO2 at every eventsinduction 10 min, Pneumoperitoneum 20 min, after PEEP apply 40 min, time of operation ending cerebral oxymetry, cerebral perfusion pressure record

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026