Gastroesophageal Reflux Disease
Conditions
Keywords
gastroesophageal reflux disease, GERD questionnaire, primary care setting
Brief summary
The purpose of this study is to evaluate the impact of gastroesophageal reflux disease (GERD) treatment in primary care setting on symptom control and daily life in symptomatic GERD patients, using both GERD questionnaire and clinical symptoms assessment
Detailed description
A prospective, observational study to describe symptom control and impact on daily life in patients with gastroesophageal reflux disease (GERD)
Interventions
None listed
Sponsors
AstraZeneca
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients known or newly diagnosed with GERD * Patients with typical GERD symptoms as heartburn and regurgitation for ≥2 days in the previous week * Patients, currently not treated with a proton pump inhibitor
Exclusion criteria
* Patients who have been receiving treatment with non-steroidal antiinflammatory drugs within two weeks prior the inclusion in the study * Patients with medical history of surgery of the esophagus, stomach or duodenum * Pregnant or nursing females
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percent change in intensity and frequency for each of typical GERD symptoms from baseline to week 4-6 | Day 0 to week 4-6 |
| Changes in GERD questionnaire(GERD-Q) scores from baseline to week 4-6 | Day 0 to week 4-6 |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the correlation between GERD-Q scores and symptom scores | two times |
Countries
Bulgaria
Outcome results
None listed