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CBT for Patients With Attention Deficit Hyperactivity Disorder (ADHD) and Substance Use Disorders

Investigating the Efficacy of Cognitive Behavioral Therapy in Patients With Substance Use Disorder and Comorbid ADHD. A Randomized Controlled Trial With Cognitive Behavioral Therapy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01431235
Enrollment
184
Registered
2011-09-09
Start date
2011-08-31
Completion date
2016-12-31
Last updated
2017-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention Deficit Hyperactivity Disorder, Substance Use Disorders

Keywords

ADHD, SUD, cognitive behavioral therapy

Brief summary

The purpose of this study is to determine if cognitive behavioral therapy is effective in treating ADHD symptoms in patients with substance use disorders and comorbid ADHD.

Detailed description

Attention Deficit Hyperactivity Disorder(ADHD) is an important comorbid condition in patients with substance use disorders (SUD). The prevalence of ADHD in patients with SUD is estimated 23%, and ADHD is associated with an untoward prognosis of SUD. However, adequate treatment programs for patients with ADHD and SUD are not available. Results of medication trials for patients with ADHD and SUD are disappointing, and cognitive behavioral therapy (CBT) has not yet been investigated in this population. In patients with ADHD without comorbid SUD, the results of CBT in randomized trials are positive. The purpose of this study is to investigate if CBT is effective in treating ADHD symptoms in patients with ADHD and SUD.

Interventions

BEHAVIORALcognitive behavioral therapy for treating ADHD symptoms

5 sessions of one hour CBT for treating ADHD symptoms by a trained health care worker

Sponsors

Fonds NutsOhra
CollaboratorOTHER
Arkin
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* substance use disorder * ADHD * able to comply with study activities

Exclusion criteria

* severe neurological or psychiatric diseases (for example Parkinson, dementia, psychosis, bipolar depression) which require medication * unable to read or write Dutch language

Design outcomes

Primary

MeasureTime frameDescription
self reported ADHD symptoms6 monthsDutch self report list of ADHD symptoms by Kooij and Buitelaar

Secondary

MeasureTime frameDescription
Beck depression inventory6 monthsself reported depression symptoms
Beck Anxiety Inventory6 monthsSelf reported anxiety symptoms
EQ-56 monthsSelf reported quality of living
TIC-P6 monthshealth care consumption and production loss in relation to mental health problems
Time Line Follow Back method6 monthsself-reported alcohol and drug use
Tower of London task6 monthsneuropsychological task
BART task6 monthsneuropsychological task on risk taking behavior
urine checks6 monthsurine checks on drug use
Stroop task6 monthsneuropsychological measure

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026