Anaemia
Conditions
Keywords
iron metabolism, hepcidin, dragon boating, sport-specific stress, iron, anaemia, sport
Brief summary
The purpose of the study is: * To investigate the effect of sport-specific stress in the iron metabolism of dragon boat athletes * To investigate the effects of sport-specific stress in the activity of pro-hepcidin and hepcidin
Detailed description
This investigation evaluates the effects of sport-specific stress in iron metabolism of dragon boat athletes. Recent studies showed a significant increase in hepcidin activity under exercise (Röcker L. et al.(2005): Iron regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology, S. 95, 569-571)which possibly influences the iron metabolism. In particular in this investigation the activity of pro-hepcidin and hepcidin under sport-specific stress is analysed. Therefore elite dragonboat athletes will be included to this study. Every athlete is tested once. At one exercise day from every athlete the iron metabolism especially the change of hepcidin, prohepcidin and iron before and after a specific dragonboat intervention is analysed.
Interventions
OTHERspecific dragon boating training intervention
male athletes of the german national dragon boat team performing three specific training units at one day
OTHERspecific dragon boat intervention
women athletes of the german national dragon boat team performing two specific training units and one weight lifting test at one day
Sponsors
MVZ für Laboratoriumsmedizin Koblenz
Deutscher Drachenboot Verband e.V.
University of Giessen
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* athletes performing dragon boat sport
Exclusion criteria
* acute clinically significant intercurrent diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change from Baseline in prohepcidin after performing dragonboating | pre and post exercise intervention at the same day | one meassurement of prohepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| value of reticulocytes | pre exercise | one meassurement of reticulocytes immediate before performing two to four specific dragonboat interventions |
| value of hypochromic erythrocytes | pre exercise | one meassurement of hypochromic erythrocytes immediate before performing two to four specific dragonboat interventions |
| change from Baseline in serum iron after performing dragonboating | pre and post exercise intervention at the same day | one meassurement of serum iron immediate before and within three hours after performing two to four specific dragonboat interventions at the same day |
| haematocrit | pre and post exercise intervention at the same day | one meassurement of haematocrit immediate before and within three hours after performing two to four specific dragonboat intervention at the same day |
| value of transferrin saturation | pre exercise | one meassurement of transferrin saturation immediate before performing two to four specific dragonboat interventions |
| value of ferritin | pre exercise | one meassurement of ferritin immediate before performing two to four specific dragonboat interventions |
| change from Baseline in hepcidin after performing dragonboating | pre and post exercise intervention at the same day | one meassurement of hepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day |
| value of transferrin | pre exercise | one meassurement of transferrin immediate before performing two to four specific dragonboat interventions |
Outcome results
None listed