Prognostic Relevance of High-sensitivity Troponin in Patients With Acute Decompensated Heart Failure

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01429857

Enrollment

304

Registered

2011-09-07

Start date

2010-06-30

Completion date

2012-01-31

Last updated

2013-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure

Keywords

Troponin concentration in heart failure

Brief summary

The purpose of this study is to investigate the prognostic value of admission high-sensitivity troponin in patients with acute decompensated heart failure.

Detailed description

Patients admitted for acute decompensated heart failure are included in the study. After gaining informed consent, concentrations of high-sensitivity troponin on admission and on discharge are assessed. 6 months after discharged, the incidence of clinical endpoint (mortality of all cause and of cardiovascular cause, hospitalization) is assessed by telephone contact to the patient and/or the physician. The aim of the study is to investigate the prognostic value of high-sensitivity troponin concentration for predicting death and re-hospitalization.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 89 Years

Healthy volunteers

Inclusion criteria

* Hospital admission for acute cardiac decompensation * Systolic and / or diastolic heart failure

Exclusion criteria

* Myocardial infarction in the last 4 weeks * Serum creatinine \>2.5 mg/dl * Pulmonary embolism

Design outcomes

Primary

Measure	Time frame
Time to cardiovascular death or hospitalization	6 Months Follow-Up

Secondary

Measure	Time frame
Time to all cause death or hospitalization	6 Months Follow-Up

Countries

Germany

Outcome results