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Gastrointestinal Microcirculation During Cardiopulmonary Bypass

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01425931
Enrollment
50
Registered
2011-08-30
Start date
2014-06-30
Completion date
2014-08-31
Last updated
2014-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MeSH Heading Cardiac Surgical Procedures, Tree Number E04.100.376, Tree Number E04.928.220

Brief summary

O2C is a diagnostic device for non-invasive determination of oxygen supply in microcirculation of blood perfused tissues. The optical sensor is easy to handle and guarantees reproducible examinations of local oxygen supply of tissues in clinics as well as in research. The examinations are without any strain for your patient. Determines by use of a glass fibre probe: Blood Flow in Microcirculation Capillary-Venous Oxygen Saturation Blood Filling of Microvessels Blood Flow Velocity This device makes it possible to supervise the local oxygen supply of organs and tissue. With it is possible to measure locally the amount of oxygen which is transported into the region of interest and to diagnose local oxygen consumption of an organ. O2C's novelty is monitoring the energetic metabolism of cells by measuring the oxygen uptake with an optical sensor probe. Pathological O2-supply, which can lead to angiogenesis or cell-death and subsequently to organ failure, now can be detected in an early state by use of the new sensor system. One of these new developed sensors are used to place in rectal position during extracorporeal circulation to determine the microcirculation.

Interventions

PROCEDUREHeart Lung machine

measurement of microcirculation with O2C device

Sponsors

Johann Wolfgang Goethe University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Patients on extracorporeal circulation

Exclusion criteria

* Haemorrhoidal lesions

Design outcomes

Primary

MeasureTime frame
Blood Flow in Microcirculation3 hours

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026