Does Administration of Probiotics During Infancy Increase the Caries Risk of a Child

Early Administration of Bifidobacterium Lactis BB-12 and the Caries Occurence of Children a 4 Years of Age

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01424852

Enrollment

Registered

2011-08-29

Start date

2012-01-31

Completion date

2012-12-31

Last updated

2012-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries

Keywords

Probiotics, Caries, Oral flora

Brief summary

Aim: to examine caries occurrence in children who ten years ago received a mixture of probiotics during infancy. Hypothesis: the administration of probiotics during infancy has no effect on future dental health.

Interventions

DIETARY_SUPPLEMENTProbiotics in infant milk formula

Probiotic infgant milk formula administered during the forst year of life

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

9 Years to 12 Years

Healthy volunteers

Yes

Inclusion criteria

* Child participated in the probiotic milk intervention study in early 2000 * Child lives now within 100 km from Turku

Exclusion criteria

* Child has a chronic illness affecting dental health * Child lives now outside 100 km from Turku

Design outcomes

Primary

Measure	Time frame
Caries occurence	10 years

Secondary

Measure	Time frame
Oral microbial colonization	10 years

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026