Early Oral Nutrition in Mild Acute Pediatric Pancreatitis

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01423786

Enrollment

Registered

2011-08-26

Start date

2011-08-31

Completion date

2014-07-16

Last updated

2019-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pediatric Pancreatitis

Brief summary

This is a prospective trial for children with the diagnosis of mild acute pancreatitis admitted to the hospital for continued management. Patients will be enrolled in the study within 24 hours of admission/diagnosis and will be allowed an oral diet once enrolled. Demographic, laboratory and imaging data done as standard of care will be collected and additional blood work will be sent as part of the study. Patients will be followed prospectively with regards to tolerance to oral nutrition, pain, length of stay and complications. The hypothesis is that patients that are able to tolerate early oral nutrition will have shorter length of stays and will be similar in terms of pain score ratings, readmission rates, complications and the need for invasive supplemental nutrition. Also patients that are able to tolerate early oral nutrition will have less significant elevation of biochemical markers of pancreatitis severity when compared to patients that do not tolerate early oral nutrition and historical controls.

Interventions

DIETARY_SUPPLEMENTEarly Oral Nutrition

Once enrolled in the study, patients will be allowed a oral diet that is low in fat.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

2 Years to 21 Years

Healthy volunteers

Inclusion criteria

* Diagnosis of acute pancreatitis * Enroll within 24 hours of diagnosis * At least 50% of baseline diet must be taken orally

Exclusion criteria

* Evidence of severe pancreatitis * Diagnosis of chronic pancreatitis * Patients unable to communicate pain or a desire to eat/drink

Design outcomes

Primary

Measure	Time frame	Description
Tolerance of Oral Nutrition	1 week	The time it takes for the patient to tolerate at least 50% of his/her goal oral calories while maintaining hydration as assessed by urine ouput or fluid intake

Secondary

Measure	Time frame	Description
Length of Stay	1 week	The length of time between admission for acute pancreatitis and discharge.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 8, 2026