Bone Mass, Effects of Vibration
Conditions
Keywords
bone, osteocyte, rest muscle electrical activity, whole-body vibration, sclerostin
Brief summary
The aim of this study is to investigate effects of femur exposed to unilateral vibration on the rest muscle electrical activity of contralateral hip adductors and contralateral soleus H-reflex in young adult men. This study hypothesize that femur exposed to unilateral vibration may affect the rest muscle electrical activity of contralateral hip adductors. Vibration can effectively enhance muscle strength and power. Previous studies have shown that vibration increases muscle electromyographic (EMG) activity. It has been showed that bone has an effect on the increase in muscle EMG activity caused by vibration in healthy young adults in a study. In this study, it was reported that vibrations-induced increases in muscle electrical activity of flexor carpi radialis (FCR) was related to ultradistal radius bone mineral content (BMC) and the FCR H-reflex was suppressed or depressed during vibration. This findings were reported to support the assumption that the bone exposed to cyclic mechanical loading may neuronally regulate muscle activity.
Detailed description
A total of 20 voluntaries are planned to include in this study. Vibration will be applied the right lower extremity by whole-body vibration (PowerPlate Pro). Cases will stand on vibration plate. WBV will be applied at a frequency of 40 Hz and amplitude of 2 mm for 60 seconds. WBV will be applied one session only. The rest muscle electrical activity of ipsilateral and contralateral hip adductor muscles at rest will be measured by PowerLab (data acquisition system, ADInstruments, Australia) device.The rest-EMGrms will be measured at before and during vibration. We also evaluate a change in contralateral soleus H reflex during vibration. Effects of bone on the rest muscle electrical activity will be assessed by hip bone mineral density, bone mineral content and serum sclerostin level. The right hip bone mineral density (BMD) and BMC will be evaluated by bone densitometer (Norland). Plasma sclerostin level will be measured by using Human Sclerostin ELISA kıt before and after vibration.
Interventions
OTHERWhole-body vibration
Frequency: 40 Hz, vibration amplitude: 2 mm, duration: 60 sec
Sponsors
Bagcilar Training and Research Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
MALE
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Age: 20-40 yrs * Gender: Male * Volunteer * Healthy status: Patients having hypoesthesia in his leg and Healthy subjects * Dominant hand:Right-handed
Exclusion criteria
* Bone diseases (osteoporosis, osteomalacia, paget's disease, neoplasm, etc), * Systemic diseases (cardiovascular, endocrine, infections etc), * Myopathy-tendinopathy * Lower limb joint disease * Vertigo * Obesity (BMI \>30 kg/m2) * Professional sportsman * Male doing regular sports activities * Skin disease in lower limb * Non-cooperative subject * Hemolysis of blood sample
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vibration-induced contralateral muscle electrical activity | 3 month |
Countries
Turkey (Türkiye)
Outcome results
None listed