the Effect of the Transversus Abdominis Plane (TAP) Block on the Minimal Laparotomy : a Randomized Controlled Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01418391

Enrollment

Registered

2011-08-17

Start date

2011-06-30

Completion date

2012-06-30

Last updated

2011-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer

Keywords

minimal laparotomy, TAP block, morphine consumption, post-operative analgesia

Brief summary

Transversus abdominis plane block (TAP block) is a new regional block for abdominal wall.It had been reported the effect of post-operative pain control in minor abdominal surgery, such as inguinal hernia repair and appendectomy. On the other hand, because of the accurate of the pre-operative images, the minimal laparotomy for colon cancer was accomplished. Thus, the purpose of this study is to investigate the effect, such as analgesic effect, hemodynamic stability, and post-operative morphine consumption, of TAP block in minimal laparotomy.

Detailed description

outcome measures: * Hemodynamic parameters (mean artery pressure, heart rate): recorded at time points of before induction of general anesthesia (baseline), after tracheal intubation immediately, after surgery started 1, 2, 3, 4, 5, 10, 15, 20, 25, and 30 min; then recorded them every 10 mins. * Post-operative morphine consumption: recorded morphine consumption at the time intervals of post-operative 0\ 6 h, 6\ 12 h, 12\ 24 h, 24\ 36 h, and 36\ 48 h ,respectively. The total amount of morphine consumption was also counted.

Interventions

PROCEDURETransversus Abdominis Plane block

TAP BLOCK: dosage form: 0.5% bupivacaine 75mg with 2% xylocaine 300 mg mixed dosage: total 30 ml frequency: single shot duration: 12\ 18 hours upon to the regional anesthetics choose

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Anesthesiologists physical status I-III, ≧ 18 years of age, and needed double-lumen endotracheal tube (DLT) for thoracic surger

Exclusion criteria

* increased risk for regurgitation and pulmonary aspiration, history of gastroesophageal reflux, and pregnancy * a tracheostomy or prolonged ventilation on ICU was planned, patients were also excluded

Design outcomes

Primary

Measure	Time frame
amount of post-operative morphine consumption	post-operative 48 hours

Secondary

Measure	Time frame
evaluation of post-operative pain status using visual analog scale (VAS) and superimposed face pain severity scale	post-operative 48 hours

Countries

Taiwan

Contacts

Primary ContactHung-Te Hsu, VS

hdhsu1228@hotmail.com+886-7-3121101

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026