Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Coronary Artery Disease
Conditions
Brief summary
Coronary artery disease is a major cause of death in patients with renal dysfunction Among patients who undergo coronary artery bypass grafting ,renal dysfunction is known To be a major predictor of in-hospital and remote mortality As little is known about the impact of non-dialysis-dependent renal dysfunction on short and mid term Outcomes following coronary surgery we have decided to investigate the effect of prophylactic Hemodialysis on the mortality and morbidity of the patients with ckd (stage 3,4 ) and compare these Effect with the control group
Interventions
PROCEDUREhemodialysis
3 sessions hemodialysis before CABG
Sponsors
Tehran University of Medical Sciences
Imam Khomeini Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 80\<age\>18 * ckd patients with stage 3,4 * CABG for the first time
Exclusion criteria
* age\<18 * previous CABG (coronary artery bypass grafting) * AKI(acute kidney injury) * dialysis patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| morbidity | the morbidity during the time of hospitalization until discharge (baseline) and six month later | morbidity is defined as length of hospitalization,infection rate,duration of mechanical ventilation,bleeding complications, |
Secondary
| Measure | Time frame |
|---|---|
| mortality | from the time of CABG (baseline) until six months later |
Countries
Iran
Contacts
Primary ContactMohamamd R khatami, MD
Backup ContactRoghieh Borji, MD
Outcome results
None listed