Use of Maytenus Ilicifolia in the Treatment of Dyspepsia

Use of Maytenus Ilicifolia Mart. ex Reiss in the Treatment of Dyspepsia

Status

Terminated

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01408849

Enrollment

Registered

2011-08-03

Start date

2015-02-28

Completion date

2016-01-31

Last updated

2016-07-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dyspepsia

Keywords

Endoscopy, Herbal medicine, Phytotherapy

Brief summary

This study aims to evaluate the therapeutic effect of the infusion of Maytenus ilicifolia Mart. ex Reiss leaves, used for 8 weeks, on patients with dyspepsia. Primary endpoint is SODA score, secondary endpoint is endoscopic classification (Sydney).

Interventions

DRUGMaytenus ilicifolia leaves infusion

2 g of powdered leaves in 150 mL of boiling water, 3 times a day, for 8 weeks

DRUGOmeprazole

Standard therapy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \> 18 years * being literate * diagnosis of dyspepsia * initial SODA score \> or = 25

Exclusion criteria

* pregnancy * lactation * allergy to Maytenus species * fail to use the drug for 3 uninterrupted weeks * new onset serious adverse events, attributable to the drug * patient's request

Design outcomes

Primary

Measure	Time frame
SODA score	8 weeks

Secondary

Measure	Time frame
Sydney classification	8 weeks

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026