Continuous Versus Conventional Volume Management During CRRT (Continuous Renal Replacement Therapy)

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01405092

Enrollment

Registered

2011-07-29

Start date

2010-04-30

Completion date

2012-08-31

Last updated

2012-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Continuous Renal Replacement Therapy

Keywords

volume, acute kidney injury, continuous renal replacement

Brief summary

Use of on-line blood volume monitoring during continuous renal replacement therapy can improve volume management in acute kidney injury patients requiring renal replacement

Interventions

DEVICEuse of continuous renal replacement machine for renal replacement

usual care with volume removal during continuous renal replacement therapy

DEVICEuse of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal

blood volume monitoring device, Critline, Hemametric, USA, will be used in conjunction with continuous renal replacement to determine rate of volume removal

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with kidney injury requiring continuous renal replacement therapy and volume removal

Exclusion criteria

* unable to provide or obtain patient consent * not expected to survive 48 hours

Design outcomes

Primary

Measure	Time frame	Description
compare number of hypotensive events in treatment versus control arms	24 hour for each arm	compare the number of hypotensive events during use of crit-line monitor over 24 hour period versus during control 24 hour period

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026