Effect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01404455

Enrollment

Registered

2011-07-28

Start date

2010-12-31

Completion date

2011-08-31

Last updated

2012-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke Volume Variation

Brief summary

The investigators examined the predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure undergoing off-pump coronary artery bypass graft

Interventions

OTHERHES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading

HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading during 15 minutes after induction of anesthesia

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SCREENING

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* 1\. Age ≥ 20 * 2\. elective off-pump coronary artery bypass graft

Exclusion criteria

* 1\. arrhythmia * 2.EF \<40% * 3.valvular heart dz * 4.pul HTN * 5.PAOD * 6.lung dz * 7.NYHA IV * 8.ESRD

Design outcomes

Primary

Measure	Time frame
The predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure	30 min

Secondary

Measure	Time frame
Cut off value of stroke volume variation for predicting fluid responsiveness in patients with wide pulse pressure	30 min

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026