Blind Painful Eye, Refractory Glaucoma, Control of Pain Through Drug Injection
Conditions
Keywords
Triamcinolone, Chlorpromazine, Refractory glaucoma, Blind painful eye
Brief summary
The purpose of this study is to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of ocular pain in blind eyes.
Detailed description
The management of chronic eye pain is a constant challenge to ophthalmology. Treatment varies with the intensity of pain, and topical eye drops and contact lens therapy are effective in many patients. In refractory cases, and without vision, surgical removal of the eye through enucleation is considered classical therapy. As less invasive alternatives we have cyclodestruction and neurolytic drug injection in order to promote analgesia for a prolonged period. The purpose of this study is to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of This is a prospective study of patients with blind painful eyes not responsive to topical treatment and with no indication for evisceration seen at the Department of Ophthalmology, Hospital Governador Celso Ramos (HGCR) in 2010.
Interventions
DRUGTriamcinolone
0,3mL intravitreal injection of Triamcinolone, single dose
DRUGChlorpromazine
2,5mL Chlorpromazine retrobulbar injection, single dose
Sponsors
Hospital Governador Celso Ramos
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients treated in the period at HGCR who wanted to be part of the protocol by signing the consent form
Exclusion criteria
* patients whose follow-up period was less than three months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Pain intensity | 0, 1 month, 3 months, 6 months after procedure | Pain was measured asking the patient to graduate it in a scale from 0 to 10, 0 being no pain, 10 being the worst pain patient has experienced in life |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in Use of eyedrops before and after drug injection | 0, 1 month, 3 months, 6 months | Patient use of eyedrops before and after the procedure (yes or no) |
| Changes in Intraocular pressure (IOP) | 0, 1 months, 3 months, 6 months | IOP was measured at all times of patient evaluation |
Countries
Brazil
Outcome results
None listed