Carotenoid Response to the Intake of Vegetables and Fruits

Skin Carotenoid Response to Intake of Vegetables and Fruits Recommended by the Dietary Guidelines

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01403844

Enrollment

Registered

2011-07-27

Start date

2011-06-30

Completion date

2012-09-30

Last updated

2020-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Resonance Raman Spectroscopy for Dietary Carotenoid Intake

Keywords

resonance Raman spectroscopy, Dietary Guidelines, fruits, biomarkers, carotenoids, MyPlate, vegetables

Brief summary

The purpose of this study is to validate the non-invasive tool, resonance Raman spectroscopy for assessing vegetable and fruit consumption.

Detailed description

This study will validate the use of resonance Raman spectroscopy to assess vegetable and fruit intake by performing a controlled feeding study during which volunteers will consume a provided diet with known amounts of carotenoids in the form of fruits and vegetables.

Interventions

OTHERCarotenoid Depletion

Depletion of carotenoids using a restricted food list

OTHERCarotenoid Repletion

Carotenoid repletion with provided diet based on dietary guidelines.

OTHERNatural Repletion

Resumption of usual personal diet regimen. No restrictions.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Men and women aged 18 - 65 years * Weight stable (±5 lbs) for at least 2 months prior to the start of the study * Body mass index (BMI) between 19-30 kg/m2 * Willing to refrain from the use of nicotine and dietary supplements for the duration of the study * Willing to maintain baseline weight and physical activity levels

Exclusion criteria

1. BMI greater than 30. 2. Gastrointestinal disorders, disease, or medication that affects carotenoid absorption or storage 3. Current smoker 4. Allergies or intolerances to foods to be utilized in the study 5. Consumption of greater than an average of 1 alcoholic drink/day for women and 2/day for men, use of nutritional/sports supplements (if unwilling to discontinue during the study) 6. Pregnancy or lactating

Design outcomes

Primary

Measure	Time frame
Serum and skin levels of carotenoids in adults fed a high carotenoid diet	28 weeks

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026