Impact of Continuous Positive Airway Pressure on the Treatment of Acute Asthma Exacerbation

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01403467

Enrollment

Registered

2011-07-27

Start date

2009-04-30

Completion date

2011-01-31

Last updated

2011-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Asthma

Keywords

Bronchial disease, asthma, continuous positive airway pressure (CPAP), Bronchoconstriction

Brief summary

This current study aimed to demonstrate the effectiveness of the addition of CPAP to the current conventional therapy in terms of airway obstruction improvement in acute asthma patients.

Detailed description

Continuous positive airway pressure (CPAP) is widely used in providing ventilator support. However, its role in an acute asthmatic attack is uncertain. The purpose of this study was to compare the efficacy of CPAP when used in addition to conventional therapy with conventional therapy alone in the management of acute asthma exacerbation.

Interventions

DEVICEContinuous positive airway pressure

CPAP 8 cmH2O

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

19 Years to 75 Years

Healthy volunteers

Inclusion criteria

* aged over 18 years * known asthmatic patients visiting ED with acute exacerbation * had given their written informed consent.

Exclusion criteria

* smoking history * chronic obstructive pulmonary disease * required intubation * instability of hemodynamic or arrhythmia * unable to perform PEFR * facial abnormality * pulmonary infiltration * pregnancy.

Design outcomes

Primary

Measure	Time frame
an improvement in PEFR, as % predicted	75 mins

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026