NSAIDs in Coronary Artery Disease Patients

Non-steroidal Anti-inflammatory Drugs Impair the Platelet Inhibiting Effect of Acetylsalicylic Acid in Coronary Artery Disease Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01402804

Enrollment

Registered

2011-07-26

Start date

2011-07-31

Completion date

2013-07-31

Last updated

2013-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CAD

Brief summary

Introduction: Different groups already showed in retrospective subgroup analyses, that there is an increased risk for cardiovascular events in patients on a simultaneous ASA/NSAID treatment. Methods: Light-Transmission aggregometry Hypothesis: Simultaneous administration of different NSAIDs and ASA impair the platelet inhibiting effect of ASA.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients on a simultaneous ASA, NSAID treatment * \> 18 years

Exclusion criteria

* unconsciousness, not able to consent * reanimation, cardiac shock

Design outcomes

Primary

Measure	Time frame
Thromboxane-levels and light-transmission aggregometry in response to arachidonic acid	During hospital stay

Countries

Germany

Outcome results