Prize Contingency Management for Cocaine-Dependent Methadone Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01401270

Enrollment

280

Registered

2011-07-25

Start date

2011-11-30

Completion date

2018-05-31

Last updated

2019-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cocaine Abuse

Brief summary

The investigators will randomize 300 cocaine-dependent methadone patients to 1 of 6 conditions: (a) a control group, (b) a contingency management condition that arranges a 100% probability of winning a prize with each draw and has 3 prize categories, (c) a contingency management condition that arranges a 31% probability of winning and has 3 prize categories, (d) a contingency management condition that arranges a 100% probability of winning and has 7 prize categories, (e) a contingency management condition that arranges a 31% probability of winning and has 7 prize categories, or (f) usual prize contingency management with a 50% probability of winning from 3 prize categories. Magnitudes of reinforcement will be identical across conditions, but lower overall probability conditions arrange for greater chances of winning larger magnitude prizes. The investigators expect that the new contingency management conditions will reduce cocaine use relative to the control condition, that 31% probability conditions will decrease drug use relative to 100% conditions, and that 7-prize category conditions will reduce drug use compared to 3-prize category conditions. In addition, the 31%/7-category condition is expected to be most efficacious. Results will be instrumental for further developing prize contingency management to improve outcomes of cocaine-dependent methadone patients.

Interventions

BEHAVIORALprize contingency management

Participants earn the chance to win prizes for the targeted behavior, cocaine abstinence.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \> 18 years * current DSM-IV diagnosis of cocaine dependence * enrolled at the clinic for \>3 months * on a stable dose of methadone (no changes) for \>1 month and not requesting a dose alteration * submitted \>1 clinic cocaine positive sample in the last 6 months * English speaking * pass a quiz related to understanding the informed consent form

Exclusion criteria

* serious, uncontrolled psychiatric illness * significant cognitive impairment * in recovery from pathological gambling

Design outcomes

Primary

Measure	Time frame
longest continuous period of cocaine abstinence	three months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026