Hypertrophy, Inflammation, Muscle Composition, Sarcopenia
Conditions
Keywords
Skeletal muscle lipid content, whole muscle volume, fasting glucose, insulin, blood urea nitrogen
Brief summary
This study is designed to assess the effect of a diet-controlled nutrition program utilizing an egg-based higher protein diet on muscle composition and size, and indices of metabolic health and markers of systemic inflammation in older men and women who are slightly overweight.
Interventions
DIETARY_SUPPLEMENTDietary Protein Intake
Dietary Protein Intake This is a 12-week randomized,prospective study incorporating a dietary intervention in which subjects will consume either higher protein(HP:1.4g protein•kg-1•d-1) or normal protein diet (NP:.8g protein•kg-1•d-1)
Sponsors
Purdue University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
55 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Men and Women between the ages of 55-80 * Body Mass Index between 27-35 * Non Diabetic * Normal liver, kidney and heart functions within 10% of clinical normalcy * Not currently following a weight loss or other special /non balanced diets * weight stable
Exclusion criteria
* fasting glucose \> 110 mg/dl * blood pressure \> 160/110 mm Hg * plasma total cholesterol \> 260 mg/dl * LDL-cholesterol \>160mg/dl * triacylglycerol\>400 mg/dl * \>than 1 hour/week of habitual aerobic and /or resistance exercise * Currently taking prescribed blood thinners
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Effects of Increased, Egg-Based Protein Intake on Muscle Composition, Metabolic Health and Systemic Inflammation in Obese, Older Adults | December 31, 2013 | Anticipated subject recruitment completion |
Countries
United States
Outcome results
None listed