Upper Respiratory Tract Infections
Conditions
Keywords
Upper Respiratory Tract Infections, Echinacea, viral infections
Brief summary
Acute upper respiratory tract infections are the most commmon infections in children and are associated with complications such as acute otitis media, sinusitis and pneumonia. Echinacea is widely used for treatment of upper respiratoty tract infections. The aim of this study is to evaluate its efficacy as prophilaxis in children 1-5 years old.
Interventions
DRUGEchinacea
0.5ml daily for children 1-2 years old and 2ml daily for children 2-5 years old
DRUGPlacebo
Placebo (0.5ml daily for children 1-2 years old and 2ml daily for children 2-5 years old) for 3 months
Sponsors
Hormozgan University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
1 Years to 5 Years
Healthy volunteers
Yes
Inclusion criteria
* Childrens 1-5 years old
Exclusion criteria
* Wheezing in previous 3 months requiring bronchodilatator * History of hyperactive reactive airway * using steroid or Echinacea * chronic pulmonary of cardiac disease * Acute respiratory disease within one week before study * Allergic rhinitis * Allergy to Echinacea * avoiding to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| occurrence of upper respiratory tract infection diagnosed by physician according to history and physical examination and laboratory tests if was necessary | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects | 6 months |
Countries
Iran
Outcome results
None listed