Osteoarthritis of the Knee
Conditions
Keywords
osteoarthritis, exercise
Brief summary
The purpose of this research is to determine whether computer-based telephone counseling will improve adherence to strength training in a population of elders with knee osteoarthritis.
Interventions
BEHAVIORALTLC
Computer-based telephone linked communication will be used to counsel subjects to adhere to their exercise program over time.
Sponsors
U.S. Department of Education
Boston University Charles River Campus
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* osteoarthritis of the knee (ICD-9 Code of 715.16, 715.09 or 715.9) * lives within interstate 95 * age 55 or older * English speaking
Exclusion criteria
* Stroke or heart attack in last 3 months * Treatment for cancer * Severe systemic disease * Medical condition that limits physical activity * Inflammatory arthritis * Plans for knee replacement * Dementia or inability to follow exercise instructions and TLC system
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Self-report measure of exercise adherence over the last 3-months on a numeric rating scale | 24 month | Exercise adherence was assessed by the single self-report item How would you rate your level of adherence to the prescribed BOOST exercise program, over the last 3 MONTHS? Participants selected a number from 0 (not at all) to 10 (completely as instructed). Higher scores reflect better adherence. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 24 -month change in self-report of pain and function using the WOMAC index | post the 1-month exercise class, 24 months | The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is a self-administered questionnaire consisting of 24 items divided into 3 subscales: Pain (5 items): during walking, using stairs, in bed, sitting or lying, and standing upright Stiffness (2 items): after first waking and later in the day Physical Function (17 items): using stairs, rising from sitting, standing, bending, walking, getting in/out of a car, shopping, putting on/taking off socks, rising from bed, lying in bed, getting in/out of bath, sitting, getting on/off toilet, heavy domestic duties, light domestic duties Responses to individual questions \[between 0 (extreme) and 4 (None)\] are summed to a raw score ranging from 0 (worst) to 96 (best) and then normalized to a WOMAC Score of between 0 (worst) to 100 (best). The difference in pain and function subscale values between the measures following the exercise class and the 24-month follow-up were used for secondary outcomes. |
| Quadriceps strength | Change in quadriceps strength from baseline to 24 months. | Isokinetic quadriceps strength will be assessed with a Biodex |
| Timed Physical Function tasks | Change in timed physical function task over 24 months | Timed physical function tasks will include a timed get up and go, timed stair ascent and descent, and a 5 and 10 chair stand time. We will examine the association of adherence, as a dichotomous and continuous variable, to change in timed physical function using logistic and linear regression, respectively. |
| Exercise quality | Average measure of exercise quality over 24 months | The outcome will be assessed at the end of the 24 month follow-up period as the number of calendar periods (1 month per calendar period) that the participant exercises at least half the number of prescribed sessions (a minimum of 6 out of 12 over a 4 week period) with the agreed upon level of intensity. |
Countries
United States
Outcome results
None listed