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Effects of Motor Cognitive Training on Functional Loss After Osteoporotic Wrist Fractures

Effects of Motor Cognitive Training on Functional Loss Through Immobilization After Osteoporotic Distal Radius Fractures: a Randomised Clinical Pilot Study in Elderly Patients

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01394809
Acronym
PROFinD-TP4
Enrollment
27
Registered
2011-07-14
Start date
2010-08-31
Completion date
2014-10-31
Last updated
2014-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporotic Distal Radius Fracture

Keywords

osteoporosis, wrist fracture, mental practice, mirror therapy, immobilization, elderly

Brief summary

The therapy results after distal radius fracture especially of elderly patients are often suboptimal. The central problem results from the inevitable, 3-6-weeks immobilization, which leads to reduction in ROM of the wrist, deterioration of muscle strength as well as malfunction of fine motor skills and coordination. Currently, there are no adequate proactive strategies to counteract these immobilisation problems. Hence the overall aim of our research project is to investigate the therapeutic potential of a motor-cognitive therapy on hand function after distal radius fracture. On the one hand the pilot study should provide information about the level of recruitment rate necessitated for an adequate sample size which allows reliable evidence for the therapy effects. On the other hand we want to evaluate the sensitivity and adequacy of the assessment instruments. The pilot is conceived as a controlled, randomised, longitudinal intervention study over 6 weeks with 3 groups. One experimental group imagine movements and actions without executing them. A second experimental group performs mirror training, in which visual feedback through a mirror activates additionally the contralateral hemisphere. The control group receives therapy as usual. There are three key domains to be analysed: function (PRWE), impairment (ROM, strength) and participation in social life/life quality (DASH, EQ5D).

Interventions

BEHAVIORALmotor cognitive therapies

pre-test; 6 weeks intervention: week 1-3: 5 times per week 60 minutes a day. Week 4-6: 3 times per week 60 minutes a day; post-test; follow-up)

Sponsors

German Federal Ministry of Education and Research
CollaboratorOTHER_GOV
University of Stuttgart
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
FEMALE
Age
65 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* wrist fracture * age 65 and older

Exclusion criteria

* unstable medical conditions which preclude surgical intervention (ASA 5) * Patients who do not live independently (nursing home) * Patients with an open fracture * Associated soft tissue or skeletal injury to the same limb * Cognitive impairment (6CIT \< 10)

Design outcomes

Primary

MeasureTime frameDescription
Patient pain and disability12 weeksPatient Rated Wrist Evaluation (PRWE)

Secondary

MeasureTime frameDescription
subjective hand function12 weeksDisabilities of the Arm and Shoulder (DASH)
objective measurements12 weeksRange of motion measurements & grip strength
subjective well-being12 weeksEQ5D

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 19, 2026