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Epigenetics of Posttraumatic Stress Disorder and Somatoform Disorders in the Course of Psychotherapy

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01391897
Acronym
TREPS
Enrollment
300
Registered
2011-07-12
Start date
2011-01-31
Completion date
2012-09-30
Last updated
2011-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychiatric Disorder, PTSD, Somatoform Disorders

Keywords

somatoform disorders, PTSD, epigenetics, psychotherapy, psychosomatics

Brief summary

This reported observational clinical study aims at identifying epigenetic markers in a sample of patients undergoing high dose inpatient psychotherapy suffering from a variety of psychiatric/psychosomatic diseases such as somatoform disorders, posttraumatic stress disorder (PTSD), depression, anxiety disorders and eating disorders. The exact epigenetic markers that will be traced are yet to define. The investigators believe that 1. Epigenetic patterns found in the group of psychiatric patients show differences from healthy controls 2. Different diagnosis show differences in epigenetic patterns as well 3. Epigenetic patterns correlate to the severity of the psychosocial disorder as measured in interviews or psychometric ratings 4. Epigenetic patterns can change under inpatient high dose psychotherapy 5. Changes correlate to clinical psychometric variables.

Interventions

BEHAVIORALpsychotherapy

multimodal complex psychotherapy

Sponsors

Hannover Medical School
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* informed consent given by the patient * adulthood to 65 years * stabel physical health * at least fluent in German language (as it is a group-therapy)

Exclusion criteria

* psychiatric disorder such as substance addiction, psychosis, schizophrenia. * insufficient understanding of the terms and conditions of the study * insufficient emotional stability to fill out the psychometric forms required for the study.

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026