Efficacy Study of Minoxidil Lotion Versus Combined Minoxidil and Finasteride Lotion to Treat Male Pattern Hair Loss

Efficacy of 3% Minoxidil Versus Combined 3% Minoxidil and 0.1% Finasteride for Male Pattern Hair Loss: a Randomized, Double-blinded, Comparative Study

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01391156

Enrollment

Registered

2011-07-11

Start date

2011-03-31

Completion date

2012-03-31

Last updated

2012-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenetic Alopecia

Keywords

minoxidil, finasteride, topical, lotion, male pattern hair loss, androgenetic alopecia

Brief summary

The purpose of this study is to compare the efficacy of 3% Minoxidil lotion and 3% Minoxidil with 0.1% Finasteride lotion for 6 months in male pattern hair loss.

Interventions

DRUG3%Minoxidil lotion

3% Minoxidil lotion apply two times a day

DRUG3% Minoxidil with 0.1% Finasteride lotion

3% Minoxidil with 0.1% Finasteride lotion apply two times a day.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

MALE

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* male, age 18-15 years * androgenetic alopecia grade 3V to 5 ( Norwood-Hamilton classification)

Exclusion criteria

* use minoxidil in 6 months * use finasteride in 12 months * use ketoconazole, tar, selenium shampoo, topical tretinoin, topical steroid in 2 weeks * seborrheic dermatitis or psoriasis on scalp * history of allergy to minoxidil, finasteride

Design outcomes

Primary

Measure	Time frame	Description
The mean change of hair count from baseline and 6 months	baseline and 6 months	Total hair count on the vertex is measured on 1 cm2 circular area. The mean change in hair count is compared at baseline and 6 months.The significance of change is determined by Unpaired t Test.

Secondary

Measure	Time frame	Description
Global photographic assessment by dermatologists	baseline and 6 months	Photographs of the vertex scalp are taken at baseline and 6 months. A panel of 3 dermatologists assesssed the change in hair growth using a 7-point scale.

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026