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Therapeutic Effects of Neurofeedback in Anorexia Nervosa

Therapeutic Effects of Alpha-neurofeedback in the Treatment of Anorexia Nervosa

Status
Completed
Phases
Phase 1Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01390493
Enrollment
12
Registered
2011-07-11
Start date
2010-10-31
Completion date
2014-11-30
Last updated
2015-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia Nervosa

Keywords

neurofeedback, alpha, anorexia nervosa

Brief summary

The purpose of this study is to determine whether neurofeedback training can significantly reduce the symptoms of anorexia nervosa (AN) with focus on changes in personality and psychological well-being. The primary aims of this study include: 1. To examine whether AN patients are able to control their alpha-activity through neurofeedback. 2. To examine the effects of neurofeedback on symptomatology and personality variables in AN patients. 3. To examine the long-term effects of neurofeedback in the treatment of AN.

Detailed description

The aim of the present study is to investigate the impact of EEG frequency band biofeedback (neurofeedback) training on EEG topography and symptomatology of patients suffering from anorexia nervosa (AN). There is evidence that alpha-neurofeedback leads to an increase in positive therapy outcome in clinical populations by changing long-lasting EEG frequency patterns. The use of an EEG-guided relaxation paradigm has been shown to be associated with well-being and improvements in pathology of psychiatric patients. In the present study the effects of alpha-training on EEG activity, mood, personality, well-being, blood parameters, and heart frequency will be evaluated in a sample of anorectic girls (12-18 years). The subjects are trained with at least 10 sessions alpha-neurofeedback, in order to enhance individual alpha frequency, with spectral resting EEG, EKG, blood samples, ERP-measures and psychometric measures assessed before and after training. Neurofeedback is conducted over a period of five weeks, with each participant receiving two training sessions per-week. Neurofeedback is administered using USBAmp-EEG system. For better surveillance of training effects there are two non-treatment control groups. A patient group receiving conventional therapy programme of the Psychosomatic Division of the Pediatric Department at the University Hospital Graz and a healthy control group. A twelve-week follow-up study is carried out in order to document long-term effects of alpha-neurofeedback training in AN patients.

Interventions

training of individual alpha frequency, 10 sessions, each 15 min

Sponsors

Medical University of Graz
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
12 Years to 18 Years
Healthy volunteers
Yes

Inclusion criteria

* anorexia nervosa diagnosed by ICD-10

Exclusion criteria

* epilepsy or other brain organic diseases

Design outcomes

Primary

MeasureTime frameDescription
brain activity in the alpha band10 sessions neurofeedbackmeasuring selected variables pre/posttraining and follow-up and on 10 points of measurement (10 sessions neurofeedback)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026