Prevalence of CVC-associated Sepsis and Use of Blood Cultures in Berlin - Brandenburg

Retrospective Analysis of Proven Bacteremia, CVC-associated Infections and Sepsis

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01388686

Enrollment

Registered

2011-07-07

Start date

2009-08-31

Completion date

2015-11-30

Last updated

2016-11-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacteremia

Keywords

sepsis, catheter, blood stream infection, blood culture

Brief summary

Structured web-based survey in selected hospitals with intensive care units in Berlin- Brandenburg to collect data on the overall number of blood cultures (used) and the prevalence of (positive blood cultures in patients with) CVC - associated sepsis.

Detailed description

The use of CVC represents one of the major risk factors for sepsis, a highly prevalent disease in ICUs. Blood cultures obtained prior to antibiotic administration are part of the SSC Resuscitation Bundle and essential for the outcome of the patient. The CDC criteria to diagnose sepsis do not take into account the overall number of blood cultures obtained and thus, lead to an underestimation of the true incidence of sepsis. Up to now, few data is available on the total number of blood cultures obtained and the relation to the incidence of sepsis in German ICUs.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Intensive care units of hospitals in the INABBRA alliance. * Patients with bacteremia.

Exclusion criteria

* Hospitals without intensive care unit.

Design outcomes

Primary

Measure	Time frame	Description
Total number of blood cultures drawn and total number of positive findings in ICUs	1 year	Retrospective analysis of cases with positive bloodculture among patients in ICU setting compared to the total amount of blood cultures taken in the same period of time and same hospital.

Secondary

Measure	Time frame
Prevalence on CVC - associated sepsis/CLABSIs	1 year

Countries

Germany

Outcome results