Effect of Yoga in Reducing Chemotherapy Induced Nausea and Vomiting

Comparison of Yoga Versus Relaxation on Chemotherapy Induced Nausea and Vomiting (CINV) Outcomes Following Chemotherapy

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01387841

Enrollment

120

Registered

2011-07-06

Start date

2010-05-31

Completion date

2013-01-31

Last updated

2013-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer, Chemotherapy-induced Nausea and Vomiting, Lymphomas, Malignant Female Reproductive System Neoplasm

Keywords

yoga, chemotherapy, nausea, vomiting

Brief summary

* This randomized controlled three arm study compares the effects of a yoga intervention with jacobsons progressive muscle relaxation training and only standard of care in chemotherapy naive cancer patients. * This study will also assess the neurophysiological correlates of nausea and vomiting and assess if effects of intervention on nausea and vomiting outcomes are mediated by changes in gastric motility (electrogastrogram) or stress arousal (cardiac autonomic function and sympathetic skin response) or self reported anxiety.

Interventions

BEHAVIORALyoga

Postures,relaxation techniques

BEHAVIORALJacobsons PMRT group

jacobsons Progressive muscle relaxation training involving 16 muscle groups

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

30 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients with gynecologic malignancies (breast, ovary) and Lymphomas. * Age between 30-70 years. * Chemotherapy naïve. * High school education.

Exclusion criteria

* Those with brain metastases * Concurring medical condition likely to influence survival * Uncontrolled diabetes and hypertension * GI metastases, peritoneal fluid, uraemia * Neurological disorders such as Parkinson's disease, myotonic dystrophy etc. * GI obstruction and past H/o abdominal surgeries. * Cognitive impairments. * Regular participation in a behavioral intervention/yoga in the last six months

Design outcomes

Primary

Measure	Time frame	Description
Effect of yoga on chemotherapy induced nausea and vomiting	4 months (prior to every cycle of chemotherapy,for 4 cycles)	This study is to evaluate the effects of yoga intervention vs. Jacobsons progressive muscle relaxation vs. standard of care only on chemotherapy induced nausea and emesis (CINV) outcomes

Secondary

Measure	Time frame	Description
Quality of life after chemotherapy	4 months	Here we evaluate the effects of yoga intervention on secondary outcomes such as quality of life and anxiety states

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026