Resection for Multiple Hepatocellular Carcinomas (HCC)

Hepatic Resection for Multiple Hepatocellular Carcinoma on Cirrhosis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01387061

Enrollment

Registered

2011-07-04

Start date

2001-06-30

Completion date

2011-06-30

Last updated

2011-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cirrhosis, Hepatocellular Carcinoma, Multiple Tumors

Keywords

liver resection, hepatic resection, intraoperative ultrasound

Brief summary

Surgical resection in patients with multiple hepatocellular carcinomas (HCC) remains controversial. The aim of this study was to investigate the outcome of a consecutive cohort of patients resected for multiple HCC, without macrovascular invasion, in order to identify clinically reliable parameters to select patients for surgery.

Interventions

PROCEDUREhepatic resection

surgical resection of the liver for multiple HCC

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* patients with multiple HCC without macrovascular invasion on liver cirrhosis

Exclusion criteria

* macrovascular invasion; * normal liver; * distant or lymphnodes metastasis

Design outcomes

Primary

Measure	Time frame	Description
Overall survival plus multivariate analysis	10 years	The primary endpoint of the study was the overall survival of patients resected for multiple HCC, and the univariate and multivariate analyses of prognostic factors for overall survival.

Secondary

Measure	Time frame	Description
Disease-free survival	10 years	The secondary endpoint was the disease-free survival.

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026