Obesity, Spinal Cord Injury
Conditions
Keywords
paralysis, paraplegia, obesity
Brief summary
Bone loss is a common secondary complication of spinal cord injury (SCI), and treatments used to reverse this condition have equivocal effectiveness. The aim of this study is to determine the effect of intense multi-modal training on bone health, body fat, and quality of life in persons with SCI. Participants will complete 6 months of training during which various measures will be obtained at 0, 3, and 6 months. Control subjects are also being recruited to complete testing but not participate in training.
Interventions
OTHERExercise training
6 months of intense multi-modal exercise consisting of vibration exercise, gait training, electrical stimulation, etc.
Sponsors
National Institutes of Health (NIH)
California State University, San Marcos
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Stable spinal cord injury below C2 * doctor's permission to participate in the study * non-pregnant
Exclusion criteria
* see above
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Bone mineral density | 6 months | Bone mineral density of the total body, knee, hip, and spine will be assessed via dual energy x-ray absorptiometry. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body fat | 6 months | Total-body and regional depots of fat and fat-free mass will also be assessed in this study. |
Countries
United States
Contacts
Primary ContactTodd A Astorino, Ph.D
Outcome results
None listed