The Telomere System in Cord Blood and in the Placenta in High Risk Pregnancies

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01384136

Enrollment

100

Registered

2011-06-28

Start date

2011-06-30

Completion date

2015-06-30

Last updated

2011-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Risk Pregnancies, Mechanisms of Telomter Homeostasis, Telomere Length

Brief summary

The telomere system stabilizes the chromosomes. Telomeres are shortened during senescence, in cases of genetic instability and secondary to stress. The investigators aim is to study the telomere system in cord blood and in the placenta immediately after the delivery in pregnancies defined as high risk pregnancies following sterss events such as placental insufficiency, preeclampsia, diabetes. The investigators intend to compare the telomere system in maternal blood to cord blood and to placental biopsies and to study the influence of different stressogenes on this system.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Third trimester post delivery * Intrauterine growth restriction * Preeclampsia * Diabetes * Control - low risk normal pregnancies

Exclusion criteria

* Patients who do not want to participate * Known HIV or Hepatitis

Countries

Israel

Outcome results