Hyperglycemia
Conditions
Keywords
Amylase, Glucosidase, Glycemic response, Sucrose, Seaweed
Brief summary
The primary endpoint of this trial will be to evaluate if a single administration in human of a lemon ice tea containing 500 mg of a polyphenol-rich algal powder is able to reduce postprandial glycemia and insulinemia.
Interventions
DIETARY_SUPPLEMENTReduction of glycemic index of ingested foods
Oral administration of the experimental lemon tea powder(56.1 g) and the placebo lemon tea powder (55.6 g) dissolved in water. Each participant will receive both treatment in a cross-over protocol design during 2 visits separated by a 2-weeks period. The day before both intervention, participants will consume a standardised meal for the supper.
Sponsors
innoVactiv Inc.
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy volunteer aged 18 to 60 * BMI between 20 and 30 * Non-smoking * Using valid contraceptive method (women of childbearing age)
Exclusion criteria
* Iodine allergy, or allergy to components of the test product or placebo or standard meal * Diabetes * Use of dietary supplements for duration of study * History of gastro-intestinal affections, anemia, major surgeries or surgeries of the stomach or digestive tract
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant reduction in postprandial glycemia | Immediately after product administration (single use) |
| Significant reduction in postprandial insulinemia | Immediately after product administration (single use) |
Secondary
| Measure | Time frame |
|---|---|
| Frequency and severity of Adverse Events as a Measure of Safety and Tolerability | First administration up to 7 days after last administration |
Countries
Canada
Outcome results
None listed