Breast Cancer, Lung Cancer, Ovarian Cancer
Conditions
Keywords
breath sample analysis, exhalation analysis, volatile organic compounds, screening, lung cancer, breast cancer, ovarian cancer, canine scent detection
Brief summary
Previous studies have shown that specially trained sniffer dogs are capable to discriminate breath samples of patients with lung cancer and healthy individuals. So far it is not known whether this differentiation is specific for lung cancer or just identifies any form of (solid) tumor. Therefore, the dog's ability to differentiate between lung cancer, breast cancer and ovarian cancer is tested.
Interventions
study participants exhale 5 times into a test tube; test tube is presented to sniffer dogs for analysis
Sponsors
Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Schillerhoehe Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* histologically confirmed lung or breast or ovarian cancer
Exclusion criteria
* other cancers * previous medical intervention within the last 14 days before gathering of the breath sample
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Specificity for Lung Cancer | breath samples will be tested within 40 days after gathering | exhalation analysis by sniffer dogs is able to differentiate breath samples of patients with lung cancer from those of patients with other (tested) cancers |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Discriminability of breast and ovarian cancer | breath samples will be tested within 40 days after gathering | exhalation analysis by sniffer dogs is able to differentiate breath samples of patients with breast cancer from those of patients with other ovarian cancer |
Countries
Germany
Outcome results
None listed