Monitoring Of Helsingborg Acute Knee Injuries (MOHAK)

Monitoring Of Helsingborg Acute Knee Injuries (MOHAK) to Understand Osteoarthritis Development After Injury.

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01382173

Enrollment

192

Registered

2011-06-27

Start date

2012-03-31

Completion date

2020-09-30

Last updated

2020-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Injury, Knee Osteoarthritis

Keywords

Knee injury, Osteoarthritis, Anterior Cruciate Ligament injury, Patellar dislocation

Brief summary

Using magnetic resonance imaging (MRI), laboratory analyses and patient reported outcomes, the overall aim of this study is to investigate structural injuries and biochemical alterations in the acutely injured knee and to relate these findings to clinical outcomes at various time points.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

12 Years to 40 Years

Healthy volunteers

Inclusion criteria

1. Age 12-40 years at inclusion (inclusion of patients younger than 18 will require parental approval) 2. A history of knee injury not more than 4 weeks prior to inclusion 3. Agreement and informed consent to participate in the study

Exclusion criteria

1. Any MRI contra-indications (such as extreme obesity, metal implants, claustrophobia etc.) 2. Pregnancy 3. A history of deep vein thrombosis (DVT) or a disorder of the coagulative system 4. General disease that effects physical function or systemic medication/abuse of steroids 5. Any other condition or treatment interfering with the completion or assessment of the trial.

Design outcomes

Primary

Measure	Time frame
Knee injury and Osteoarthritis Outcome Score (KOOS)	5 yrs

Secondary

Measure	Time frame
Radiographic osteoarthritis	5 yrs

Countries

Sweden

Outcome results