Macular Holes
Conditions
Keywords
spectral-domain optical coherence tomography, idiopathic macular hole, cone outer segment tips line, vitrectomy
Brief summary
Spectral domain optical coherence tomography (SD-OCT) was used to determine whether the repair of photoreceptor cone outer segment tips defect is significantly correlated with the visual outcomes after macular hole surgery.
Detailed description
Spectral domain optical coherence tomography (SD-OCT) was used to calculate the mean length of photoreceptor cone outer segment tips (COST) defect on 1, 3, 6, 9, and 12 months after macular hole surgery. The correlation between the mean length of COST defect and the BCVA was determined. Prognostic factors might have influenced for COST repair was also evaluated by multivariable analysis.
Interventions
PROCEDUREVitreous surgery for macular hole
Vitreous surgery for macular hole
Sponsors
Kyorin University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* macular hole patients with surgically-closed hole
Exclusion criteria
* macular hole patients failed to close hole * presence of retinal diseases including a treated rhegmatogenous retinal detachment, diabetic retinopathy, and high myopia with an axial length \>27.0mm or refractive error \> -8.0 diopters(D). * patients who were not followed at least 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual acuity | one year | Preoperative, postoperative 1, 3, 6, 9, 12 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Integrity of cone outer segment tips line | one year | The mean length of cone outer segment tips defect on preoperative and postoperative 1, 3, 6, 9, and 12 months with spectral domain optical coherence tomography |
Countries
Japan
Outcome results
None listed