Neighborhoods, Networks, Depression, and HIV Risk

The Impact of Neighborhoods, Networks, and Depression on Drug Users' HIV Risk

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01380613

Acronym

Workshop

Enrollment

965

Registered

2011-06-27

Start date

2007-09-30

Completion date

2013-07-31

Last updated

2013-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV, Depression, Drug Use

Keywords

HIV, depression, drug use,, risk reduction

Brief summary

The goal of this study is to examine how social networks, neighborhood, and depression are related to HIV risk. The intervention is designed to train individuals to cope with feelings of depression or stress as a way to reduce their risk for HIV.

Detailed description

This study included implementation and evaluation of a small group, randomized controlled, phase II intervention to reduce depressive symptoms and HIV risk behaviors among inner city drug users. The intervention included elements of cognitive behavioral therapy (CBT) for depression among impoverished individuals, emphasizing depressive cognitions and behaviors theorized to be associated with depression and with HIV risk behaviors among mildly to moderately depressed drug users. In addition, the study examined active drug users' social and environmental pathways to depression and subsequent HIV risk behaviors. Specifically, we will hypothesized mediating/moderating effects of neighborhood characteristics, social network factors, and individual level factors on depressive symptoms and HIV risk behaviors.

Interventions

BEHAVIORALWorkshop

10 session intervention

BEHAVIORALWorkshop control

1 session intervention on standard HIV/STD information

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 55 Years

Healthy volunteers

Inclusion criteria

1. 18-55 years old 2. HIV Risk Behavior: 3a. Injected drugs more than 3 times in the past week OR 3b. Snorted/sniffed heroin or cocaine or smoked crack in the past 6 months AND had 1 of the following sex risks in the past 6 months: i) 2 or more sex partners ii) Had a sex partner who injected drugs iii)Had a sex partner who smoked crack iv) Had a sex partner who was HIV+ 4\. Willingness to attend group sessions

Exclusion criteria

1. Enrolled in another HIV behavioral intervention or depression study in past the 3 years 2. Enrolled in another Lighthouse study in past the 5 years 3. Enrolled in the formative research (Phase 1) or pilot (Phase 2) of the current project.

Design outcomes

Primary

Measure	Time frame
Change from Baseline in Depressive Symptoms Measured by the CESD Scale at 6 months	6 months
Change from Baseline in Depressive Symptoms Measured by the CESD Scale at 12 months	12 months

Secondary

Measure	Time frame
Change from Baseline in Sex Risk Behavior Based on Number of Sex Partners and Condom Use at 6 months	6 months
Change from Baseline in Injection Risk Behavior Based on Sharing Needles, Cookers, and Cotton For Injection and Drug Splitting at 6 months	6 months
Change from Baseline in Sex Risk Behavior Based on Number of Sex Partners and Condom Use at 12 months	12 months
Change from Baseline in Injection Risk Behavior Based on Sharing Needles, Cookers, and Cotton For Injection and Drug Splitting at 12 months	12 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026