Continuous Infraclavicular Nerve Blocks: Needle Versus Catheter Local Anesthetic Bolus

Status

Withdrawn

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01377545

Enrollment

Registered

2011-06-21

Start date

2013-01-31

Completion date

2013-01-31

Last updated

2013-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nerve Block

Keywords

Infraclavicular, Nerve Block, Needle, Perineural Catheter, Volunteer, Upper Extremity Nerve Block, Sensation, Strength

Brief summary

The investigators propose to test the hypothesis that when placing a perineural catheter for a continuous peripheral nerve block, injecting the initial local anesthetic bolus via the insertion needle results in a faster-onset sensory block than injecting the initial bolus via the perineural catheter. The study results will help define the optimal local anesthetic bolus introduction technique-needle versus catheter-for peripheral nerve blocks when placing a perineural catheter.

Detailed description

Specific Aim: The investigators propose to test the hypothesis that when placing a perineural catheter for a continuous peripheral nerve block, injecting the initial local anesthetic bolus via the insertion needle results in a faster-onset sensory block than injecting the initial bolus via the perineural catheter. The study results will help define the optimal local anesthetic bolus introduction technique-needle versus catheter-for peripheral nerve blocks when placing a perineural catheter.

Interventions

PROCEDURELocal Anesthetic given via perineural catheter for infraclavicular nerve block.

Patients will be randomized to receive 30mL of Lidocaine via Catheter for an infraclavicular nerve block on one side (right or left) and via needle on the other side. Sensory and strength will be tested following local anesthetic administration.

PROCEDURELocal Anesthetic given via needle for infraclavicular nerve block

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* age ≥ 18 years * willing to have bilateral infraclavicular blocks/catheters placed

Exclusion criteria

* current daily analgesic use * opioid use within the previous 4 weeks * any neuro-muscular deficit of either upper extremity * body mass index \> 30 kg/m2 * weight \< 50 kg \[100 lbs\] * pregnancy * incarceration

Design outcomes

Primary

Measure	Time frame	Description
Sensory Level	120 minutes	EKG pads will be positioned in the 5 major nerve distributions distal to the elbow, ensuring placement is equivalent bilaterally. The primary endpoint will be the time, in minutes, until all 5 nerve territories record \> 60 mA, or 120 minutes-whichever occurs first-since 60 mA is estimated to be equivalent to a surgical incision.

Secondary

Measure	Time frame	Description
Grip Strength	120 Minutes	Evaluated using a portable isometric force dynamometer to measure the maximum voluntary isometric contraction (MVIC) of the hand/fingers. Subjects will be asked to take 2 sec to come to maximum effort, maintain this effort for 3 sec, and then relax.
Sensory level for individual nerves	120 Minutes	Evaluated using transcutaneous electrical stimulation (TES) in the same manner as described for the primary end point.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026