Step Up Versus Step Down in Controlled Ovarian Stimulation

Step Up Versus Step Down in Controlled Ovarian Stimulation for Intrauterine Insemination. A Controlled Randomised Trial.

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01376999

Enrollment

158

Registered

2011-06-20

Start date

2010-04-30

Completion date

2014-02-28

Last updated

2017-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

No Explained Sterility

Keywords

Sterility, FSH-r, intrauterine insemination, unexplained sterility

Brief summary

The aim of the study is to evaluate if the Step up protocol is equal or superior regarding efficacy and security than the step down protocol. In couple submitted two intrauterine insemination.

Interventions

DRUGFSH-r (Follicule stimulate hormone)

Step-Up: 75 IU FSH-r Step-Down: 150 FSH-r

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 37 Years

Healthy volunteers

Inclusion criteria

* Women with unexplained sterility with needs of intrauterine insemination.

Exclusion criteria

* Contraindications to intrauterine insemination.

Design outcomes

Primary

Measure	Time frame
Ovulation rate	1 month

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026