Acute Renal Failure
Conditions
Keywords
acute renal failure, cerebrovascular autoregulation, transcranial Doppler, continuous veno-venous hemodialysis
Brief summary
The aim of the study is to characterize the influence of continuous veno-venous hemodialysis on the cerebrovascular autoregulation.
Detailed description
Patients at the intensive care unit who suffered acute renal failure with the need of continuous veno-venous hemodialysis will be investigated with continuous veno-venous hemodialysis and in a time window without continuous veno-venous hemodialysis to investigate the influence of continuous veno-venous hemodialysis on the cerebrovascular autoregulation.
Interventions
PROCEDUREcontinuous veno-venous hemodialysis
continuous veno-venous hemodialysis
Sponsors
Johannes Gutenberg University Mainz
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* acute renal failure * need for continuous veno-venous hemodialysis * age \>18 Years
Exclusion criteria
* Sepsis * Preexisting cerebral illness * traumatic brain injury * Meningitis or encephalitis * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from Baseline cerebrovascular autoregulation to cerebrovascular autoregulation during continuous veno-venous hemodialysis | 1 Year | Is there an influence of continuous veno-venous hemodialysis at the cerebrovascular autoregulation, which would be a side effect with limiting use in patients with brain injury or the need of intensive monitoring of cerebral perfusion pressure in this patients. |
Countries
Germany
Outcome results
None listed