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Acceptability and Effectiveness of Household Water Treatment in Reducing Diarrhea Among Under Five Children

Acceptability and Effectiveness of Household Water Chlorination in Reducing the Prevalence of Diarrhea Among Under Five Children in Eastern Ethiopia

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01376440
Enrollment
845
Registered
2011-06-20
Start date
2011-06-30
Completion date
2011-10-31
Last updated
2012-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Diarrhoea

Keywords

three or more loss stools in 24 hours

Brief summary

The Millenium development goals (MDGs) call for reducing by half the proportion of people without sustainable access to safe drinking water. This goal was adopted in large part because safe drinking water has been seen as critical to fighting diarrheal disease. Source protection is considered the main intervention area to achieve this goal. However, research worldwide that has shown that even drinking water which is safe at the source is subject to frequent and extensive fecal contamination during collection, storage and use in the home. This contamination is through the introduction of cups, dippers or hands, contamination by flies, cockroaches, and rats. Even piped water supplies of adequate microbial quality can pose infectious disease risks if they become contaminated due to unsanitary collection, storage conditions and practices within households. To reduce this problem, point-of-use water treatment has been advocated as a means to substantially decrease the global burden of diarrhea and to contribute to the MDGs. However, research indicates that there are many unanswered questions around Household water treatment (HWT) that require small or medium scale epidemiological studies and randomized controlled trials, especially with regard to effectiveness, acceptability and identifying suitable target populations. Some of the most urgent questions to be resolved are:(1) How much of the currently cited disease reduction of HWT is due to bias? (2) What is the effect of HWT on nutritional status (weight gain and growth)?(3) At which populations should HWT be targeted? (4) Is it acceptable and sustainable in poor communities where the risk of diarrheal disease is high. hypothesis: Do household water treatment with chlorine reduce diarrhea among underfive children? hypothesis: Do household water treatment with chlorine acceptable in the community?

Interventions

OTHERhousehold water treatment

household water treatment with 1.25% sodium hypochlorite

Sponsors

Haramaya Unversity
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
1 Months to 59 Months
Healthy volunteers
No

Inclusion criteria

* All children under five years of age in the randomly selected clusters of Kersa district

Exclusion criteria

* seriously sick children in the randomly selected clusters of Kersa district

Design outcomes

Primary

MeasureTime frameDescription
To assess the prevalence of diarrhea among under five childrenfour monthsweekly visit of the household for the presence of diarrhoea among underfive for four months in both the intervention and control groups

Secondary

MeasureTime frameDescription
To assess the weight gain among the intervention and control groups of under five childrenAt the beginning and end of the study ( 4 months interval)This is designed to assess whether there is weight gain (objective outcome) in children assigned to the intervention group compared to the control group. It is supplement to the prevalence of diarrhea which is subjective outcome for this study
Residual chlorine testfour monthsThe use of the intervention (1.25% hypochlorite) is confirmed by the testing the residual chlorine weekly for for months from each household assigned in the intrevention group

Countries

Ethiopia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 10, 2026