Hypertensive Disorders of Pregnancy in Adolescence and Primipaternity

Hypertensive Disorders of Pregnancy in Adolescence and the Primipaternity Concept. Cases and Control Trial

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01374477

Enrollment

110

Registered

2011-06-16

Start date

2012-06-30

Completion date

2016-01-31

Last updated

2015-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preeclampsia

Keywords

Preeclampsia in Adolescence, Adolescent, Primipaternity

Brief summary

Hypertensive disorders of pregnancy are one of the most frequent complications of pregnancy, being a serious health problem around the world. Previous studies have suggested that there is an association between a short period of exposure to paternal sperm of a new sexual partner and the development of an immunological reaction that could trigger a hypertensive disorder of pregnancy. For this reason we want to study the relationship between the primipaternity concept (exposure to male antigens present in semen over a short period of time previous to the pregnancy) and the development of preeclampsia in adolescents.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

No minimum to 19 Years

Healthy volunteers

Inclusion criteria

* 19 year old or less * Pregnancy \> 24 weeks at the moment of delivery

Exclusion criteria

* 20 years old or more. * Pregnancy \< 24 weeks at the moment of delivery

Design outcomes

Primary

Measure	Time frame	Description
Presence of a primipaternity factor	Two months	The presence of primipaternity factor. They include: 1. Sexual Cohabitation (timeframe between first sexual intercourse and pregnancy \< 4 months)without the use of a barrier contraceptive. 2. Oral sex with ejaculation (previous to pregnancy \< 4 months).

Secondary

Measure	Time frame	Description
Maternal complications	Two months	Presence of a complication related to preeclampsia: abruptio placenta, HELLP syndrome, eclampsia.

Countries

Panama

Contacts

Primary ContactLeisa Rosas, MD

lcr10@hotmail.com66146306

Backup ContactOsvaldo Reyes, MD

investigacionmaternidadhst@yahoo.com65655041

Outcome results