The Effect of Dexmedetomidine on Postoperative Analgesia

Assessment of the Effect of Dexmedetomidine in the Management of Postoperative Pain When Combined With Fentanyl in the Patient-controlled Analgesia

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01373021

Enrollment

Registered

2011-06-14

Start date

2011-06-30

Completion date

2012-02-29

Last updated

2012-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer, Rectal Cancer

Brief summary

The purpose of this study is to determine whether additional Dexmedetomidine to patient controlled analgesia can reduce fentanyl consumption.

Interventions

DRUGFentanyl

Fentanyl 2500mcg+NS50ml

DRUGDexmedetomidine

Fentanyl 2500mcg+Dexmedetomidine 500mcg + NS 45ml

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 74 Years

Healthy volunteers

Inclusion criteria

* Elective surgery for colon cancer

Exclusion criteria

* Liver disease * Kidney disease * Allergy for study drugs * Inability to receive patient controlled analgesia

Design outcomes

Primary

Measure	Time frame
total amount of administered fentanyl	during first 24 hours after surgery

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026