Serum IGF-II and Cancer: Can IGF II Levels be Used to Monitor and Screen Patients Specifically for Cervical Cancer

Phase 1 of Serum IGF II and Cancer: Can IGF II Levels be Used to Monitor and Screen Patients Specifically for Cervical Cancer

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01371695

Enrollment

Registered

2011-06-13

Start date

2011-05-31

Completion date

2013-09-30

Last updated

2011-06-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer, Cervical Intraepithelial Neoplasia II, Cervical Intraepithelial Neoplasia III

Keywords

IGF-II levels

Brief summary

The purpose of this study is to determine whether Insulin-like Growth Factor II is elevated sufficiently to detect Cervical Intraepithelial Neoplasia II (CIN II), Cervical Intraepithelial Neoplasia III (CIN III), and cervical cancer.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* Age 18 - 75 years * Female * Normal medical history * Medical history of a single type of cancer confirmed by biopsy or equivalent criteria * Squamous cell carcinoma of organs other than cervix * Adenocarcinoma * Medical history of inflammatory disease * May be pregnant * Pap smear positive for Cervical Intraepithelial Neoplasia II or III * Squamous cell cervical cancer confirmed by biopsy * Informed consent * Willingness to submit a blood sample by venipuncture * Willingness to submit a second blood sample if necessary

Exclusion criteria

* Age \< 18 or \> 75 years * Medical history of cancer other than cervical cancer, Non-islet-cell tumor hypoglycemia, Growth hormone deficiency, Acromegaly, Hepatoma, inflammatory disease in addition to confirmed CIN and cervical cancer

Countries

United States

Outcome results