Effects of Exposure to Biomass-burning Air Pollution on Lung Function, Heart Rate Variability and Inflammatory Markers in Sugarcane Workers

Effects of Exposure to Outdoor Air Pollution From Biomass Burning on Lung Function, Heart Rate Variability and Systemic Inflammatory Blood Markers in Sugarcane Workers

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01371188

Enrollment

222

Registered

2011-06-10

Start date

2008-12-31

Completion date

2011-02-28

Last updated

2011-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Rate Variability, Lung Function, Oxidative Stress, Systemic Inflammatory Response

Brief summary

Introduction: Non-mechanized sugar cane harvesting preceded by burning, an important and prevalent professional activity of agribusiness segment of the Brazilian economy, exposes workers and people of neighboring towns to high concentrations of pollutants and, therefore, potentially several risks to health hazards. Objectives: Assessing cardiopulmonary impacts and inflammatory markers in sugarcane workers and volunteers from a nearby town in non-harvest and harvest periods.

Interventions

None listed

Study design

Observational model

ECOLOGIC_OR_COMMUNITY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

MALE

Age

20 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* The criteria for inclusion in the study were: age between 20 and 40 years, male gender and being non-smokers (or former-smokers for at least a year and a smoking history of less than 20 pack-years).

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Lung function	six months	Measurements of lung function in pre harvest and during harvest period
Heart rate variability	six months	To evaluate parameters of heart rate variability in pre harvest and during harvest periods
Oxidative stress	six months	Measurement of blood levels of antioxidant enzymes and malonaldehyde

Secondary

Measure	Time frame	Description
Environmental evaluation	one year	Measurement of athmospheric concentration of particulate matter.

Countries

Brazil

Outcome results