Umbilical Cord
Conditions
Keywords
ultrasound, first trimester, umbilical cord
Brief summary
The primary objective of this study is to determine the detection rate of two- or three-vessel umbilical cord at the time of nuchal translucency screening between 11 and 13 6/7 weeks gestation. Hypothesis: Detection rate of the number of vessels during first trimester will be as accurate as the detection of vessels during the second trimester.
Interventions
PROCEDUREDoppler ultrasound
Ultrasound using Doppler mode to detect blood flow in umbilical cord vasculature and determine the number of vessels present
Sponsors
Medstar Health Research Institute
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Singleton or multiple-gestation pregnancies in patients presenting for NT screening between 11 and 13 6/7 weeks gestation and CRL between 45-84mm as determined at the time of the ultrasound * Age 18 and older
Exclusion criteria
* Patients who are incapable of informed consent or minors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection of the number of vessels in the umbilical cord between 11 and 13 6/7 weeks. | 11-13+6 weeks |
| Detection of the number of vessels in the umbilical cord between 18 and 23 6/7 weeks. | 18 - 23 6/7 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of transabdominal sonography at detecting vasculature of the cord between 11 and 13 6/7 weeks. | 11-13+6 weeks gestational age |
| Sensitivity and specificity of transabdominal sonography at detecting vasculature of the cord during the second trimester. | 18-24 weeks gestation |
Countries
United States
Outcome results
None listed