Fluid Responsiveness
Conditions
Keywords
pulse pressure variation, systolic pressure variation, central venous pressure, aortic blood flow velocity variation, pleth variability index
Brief summary
The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children. Children who need volume expansion will receive colloid 10 mL/kg. Blood pressure, heart rate, central venous pressure, systolic pressure variation, pulse pressure variation, delta down, aortic blood flow velocity variation, inferior vena cava diameter variation, and pleth variability index will be measure before and after volume expansion. Patients will be classified as responders to volume loading if stoke volume index increase by at least 15%.
Interventions
OTHERvolume expansion
fluid loading of 10 mL/kg colloid (voluven)
Sponsors
Seoul National University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
No minimum to 8 Years
Healthy volunteers
No
Inclusion criteria
* neurosurgery under general anesthesia * \< 8 years old
Exclusion criteria
* cardiac disease * pulmonary, renal and hepatic disease * infectious disease * hematologic and muscular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| stoke volume index | before and after volume loading (20 minutes) | Volume loading will be performed for 20 minutes. Stroke volume will be meausred before and after volume expansion |
Countries
South Korea
Outcome results
None listed